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October 31, 2023
Uncategorized

AATec Medical and Beurer enter development collaboration for inhaled Alpha-1 Antitrypsin

AATec Medical and Beurer will develop novel inhaler devices for delivering innovative, targeted therapeutics based on recombinant alpha-1 antitrypsin (AAT) to the airways Inhalatio

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by ante
October 10, 2023
Uncategorized

AATec Medical Announces Creation of Scientific Advisory Board

Leading scientific and clinical experts, Prof. Dr. Ulrike Protzer, Prof. Dr. Jan Münch, and Dr. Gerhard Scheuch, join the newly established Scientific Advisory Board The Board&#82

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by ante

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A Versatile Platform for Global Respiratory Health

Beyond NCFB, our recombinant AAT platform offers significant potential in major respiratory markets like COPD and asthma, where it targets underserved neutrophilic inflammation. It also offers significant potential in airway infections, leveraging ATL-105’s antiviral and bacteriostatic effects to reduce exacerbations. In the long-term our AAT products could help close critical care gaps in pulmonary indications including acute respiratory distress syndrome (ARDS) and Bronchiolitis Obliterans Syndrome (BOS).

Non-CF Bronchiectasis (NCFB)

Our lead indication non-cystic fibrosis bronchiectasis (NCFB) is a debilitating chronic respiratory disease marked by permanent airway enlargement and a “vicious vortex” of persistent neutrophilic inflammation and recurrent infections.

Despite its severity, there are currently treatment options are still limited for the over 3 million patients in Western countries alone. This represents a massive unment medical need and a significant market opportunity, with a peak sales potential of $1.8 billion for ATL-105 in this indication alone.

ATL-105 provides a compelling biological rationale for the treatment of NCFB, as its multimodal action directly targets the underlying drivers of tissue destruction by irreversibly inhibiting neutrophil proteases, restoring the airway’s cytokine balance.